DermProtect Barrier Defense
$140See It In Action
DermProtect Barrier Defense is an intensive moisturizer that delivers maximum hydration, replenishes natural lipids, and enhances moisture retention. Advanced technology goes even deeper to target the source of dryness by resetting and regulating skin's natural 24-hour cycle to boost daytime defense and nighttime regeneration, optimizing barrier function and rebalancing the microbiome for enhanced skin resilience.
While considered pregnancy/nursing-friendly, we recommend consulting your healthcare provider for any specific concerns.
- Lindera Strychnifolia Root Extract. Works at a cellular level to reset and regulate skin's natural 24-hour cycle so skin knows to defend during the day, and regenerate at night.
- Hibiscus Sabdariffa Fruit Extract. A hydration-optimizing ingredient that enhances lipid production and helps seal the skin barrier.
- Bacillus Ferment. Enhances natural processes to support skin cell renewal and strengthen the skin barrier.
- Epidermal Lipid Blend. Locks in moisture and creates a healthy environment for the microbiome.
- Ceramide Blend. Locks in moisture and protects against external irritants.
- Hyaluronic Acid. Attracts and holds onto moisture for lasting hydration.
Water (Aqua), Glycerin, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Cetearyl Alcohol, Pentylene Glycol, Cetyl Esters, Dimethicone, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Propanediol, Ethylhexyl Stearate, Ethylhexyl Palmitate, Glyceryl Stearate, Glyceryl Stearates, PEG-100 Stearate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Squalane, Ceramide NP, Ceramide AP, Ceramide EOP, Cocos Nucifera (Coconut) Fruit Extract, Hibiscus Sabdariffa Fruit Extract, Lindera Strychnifolia Root Extract, Caprylic/Capric Triglyceride, Santalum Album (Sandalwood) Extract, Phellodendron Amurense Bark Extract, Hordeum Distichon (Barley) Extract, Alpha-Glucan Oligosaccharide, Bacillus Ferment, Rosmarinus Officinalis (Rosemary) Leaf Extract, Astragalus Membranaceus Root Extract, Ubiquinone, Tocopherol, Ursolic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Sodium Lauroyl Lactylate, Lecithin, Phytosphingosine, Erythritol, Steareth-10, Steareth-20, Cholesterol, Dimethiconol, Dipropylene Glycol, Ethylhexylglycerin, Carbomer, Xanthan Gum, Sodium Benzoate, Citric Acid, Potassium Sorbate, Phenoxyethanol.
Orders are processed Monday through Friday, excluding weekends and major holidays. Orders are typically delivered within 5-7 business days.You may return any item purchased at full price in new or gently used condition within 30 days of purchase, by mail. Some orders may be subject to a $9.95 handling fee. Please note, some Items are final sale.More Information on Shipping + Returns
Targets:
Before & After
Smoother & Clearer Skin. More Confident You.

"Started seeing results in the first couple weeks and now after a full year of using this product I have brand new skin! My biggest insecurity is gone and I can feel confident in myself again."
"I couldn’t find anything to help treat the hyperpigmentation, uneven skin tone, and rough texture left behind from the acne scars until I discovered this absolute gem!"
"These before and after photos are from 6 months apart and without using any other products! So thankful to have found this brand!"
"I have been using these products for almost a year. I have been waiting for my face to break out again like it has done the last several winters... it hasn't happened. My skin is clearer and healthier than ever. I don't have severe itching and pain from brutal adult acne. Thank you Barefaced."

Clinically–Proven Ingredients You’ll Love
Lindera Strychnifolia Root Extract
Hibiscus Sabdariffa Fruit Extract
Bacillus Ferment
Epidermal Lipid Blend
Ceramide Blend
Hyaluronic Acid
While considered pregnancy/nursing-friendly, we recommend consulting your healthcare provider for any specific concerns.
- Lindera Strychnifolia Root Extract. Works at a cellular level to reset and regulate skin's natural 24-hour cycle so skin knows to defend during the day, and regenerate at night.
- Hibiscus Sabdariffa Fruit Extract. A hydration-optimizing ingredient that enhances lipid production and helps seal the skin barrier.
- Bacillus Ferment. Enhances natural processes to support skin cell renewal and strengthen the skin barrier.
- Epidermal Lipid Blend. Locks in moisture and creates a healthy environment for the microbiome.
- Ceramide Blend. Locks in moisture and protects against external irritants.
- Hyaluronic Acid. Attracts and holds onto moisture for lasting hydration.
Water (Aqua), Glycerin, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Cetearyl Alcohol, Pentylene Glycol, Cetyl Esters, Dimethicone, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Propanediol, Ethylhexyl Stearate, Ethylhexyl Palmitate, Glyceryl Stearate, Glyceryl Stearates, PEG-100 Stearate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Squalane, Ceramide NP, Ceramide AP, Ceramide EOP, Cocos Nucifera (Coconut) Fruit Extract, Hibiscus Sabdariffa Fruit Extract, Lindera Strychnifolia Root Extract, Caprylic/Capric Triglyceride, Santalum Album (Sandalwood) Extract, Phellodendron Amurense Bark Extract, Hordeum Distichon (Barley) Extract, Alpha-Glucan Oligosaccharide, Bacillus Ferment, Rosmarinus Officinalis (Rosemary) Leaf Extract, Astragalus Membranaceus Root Extract, Ubiquinone, Tocopherol, Ursolic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Sodium Lauroyl Lactylate, Lecithin, Phytosphingosine, Erythritol, Steareth-10, Steareth-20, Cholesterol, Dimethiconol, Dipropylene Glycol, Ethylhexylglycerin, Carbomer, Xanthan Gum, Sodium Benzoate, Citric Acid, Potassium Sorbate, Phenoxyethanol.
Free from Unwanted Ingredients

Using DermProtect Barrier Defense
Frequently Asked Questions
We can help with that! To get started, we recommend taking our skin quiz, which you can find here. The skin care quiz will guide you to the best products for your skin type.
Barefaced, and all of the other lines we carry, are considered “medical-grade” skincare (although that’s not a regulated term). Our products are formulated to be results-driven, and they’re developed by medical professionals, master formulators and expert chemists to induce change in the skin at the cellular level.
Yes, all of the products we stock are cruelty-free.