DermProtect Barrier Defense
New!
DermProtect Barrier Defense
New!

DermProtect Barrier Defense

$140
Intensive moisturizing cream for dry to very dry, sensitive and mature skin
Free shipping on orders $99+

See It In Action


DermProtect Barrier Defense is an intensive moisturizer that delivers maximum hydration, replenishes natural lipids, and enhances moisture retention. Advanced technology goes even deeper to target the source of dryness by resetting and regulating skin's natural 24-hour cycle to boost daytime defense and nighttime regeneration, optimizing barrier function and rebalancing the microbiome for enhanced skin resilience.


  • Resets and regulates skin’s natural 24-hour cycle, maximizing daytime defense and nighttime regeneration
  • Reduces skin barrier disruption and repairs skin barrier function
  • Supports a balanced microbiome and skin’s natural lipid production
  • Increases skin hydration and reduces transepidermal water loss
  • Delivers immediate and long-term hydration
  • Soothes, calms, and revitalizes dry skin
  • Optimizes skin barrier health and function to maximize the effectiveness of all skincare

  • Lindera Strychnifolia Root Extract. Works at a cellular level to reset and regulate skin's natural 24-hour cycle so skin knows to defend during the day, and regenerate at night.
  • Hibiscus Sabdariffa Fruit Extract. A hydration-optimizing ingredient that enhances lipid production and helps seal the skin barrier.
  • Bacillus Ferment. Enhances natural processes to support skin cell renewal and strengthen the skin barrier. 
  • Epidermal Lipid Blend. Locks in moisture and creates a healthy environment for the microbiome.
  • Ceramide Blend. Locks in moisture and protects against external irritants.
  • Hyaluronic Acid. Attracts and holds onto moisture for lasting hydration.

Orders are processed Monday through Friday, excluding weekends and major holidays. Orders are typically delivered within 5-7 business days.You may return any item purchased at full price in new or gently used condition within 30 days of purchase, by mail. Some orders may be subject to a $9.95 handling fee. Please note, some Items are final sale.More Information on Shipping + Returns


DermProtect Barrier Defense

Targets:

Dry Skin
Mature Skin
Sensitive Skin

Before & After

Smoother & Clearer Skin. More Confident You.

Clinically–Proven Ingredients You’ll Love

Lindera Strychnifolia Root Extract

Hibiscus Sabdariffa Fruit Extract

Bacillus Ferment

Epidermal Lipid Blend

Ceramide Blend

Hyaluronic Acid

While considered pregnancy/nursing-friendly, we recommend consulting your healthcare provider for any specific concerns.

Free from Unwanted Ingredients

  • No parabens
  • No fragrance
  • No phthalates
  • No sulfates
  • No artificial dyes
  • No mineral oil
  • No formaldehyde donors
Results-Driven Developed by a Nurse Practitioner Results-Driven Developed by a Nurse Practitioner Results-Driven Developed by a Nurse Practitioner

Using DermProtect Barrier Defense

Apply twice daily after cleansing and using all other treatment products. Smooth cream onto the face avoiding the eye area. Follow with an application of sunscreen in the morning.

How to Get Started

Use in the morning and evening after cleansing and applying all other treatment products.

Frequently Asked Questions

We can help with that! To get started, we recommend taking our skin quiz, which you can find here. The skin care quiz will guide you to the best products for your skin type.

Barefaced, and all of the other lines we carry, are considered “medical-grade” skincare (although that’s not a regulated term). Our products are formulated to be results-driven, and they’re developed by medical professionals, master formulators and expert chemists to induce change in the skin at the cellular level.

Yes, all of the products we stock are cruelty-free.